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. 2017 Oct 18;14(6):5956–5964. doi: 10.3892/etm.2017.5333

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Copyright: © Hao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effects of BM-MSCs and AD-MSCs on the activation, proliferation and apoptosis of HSCs in a co-culture system. HSCs were co-cultured with either BM-MSCs or AD-MSCs for 72 h and HSC activation, proliferation and apoptosis were examined. (A) Western blot analysis of α-SMA expression in the control and MSC-treated groups. *P<0.05 vs. control groups, ^ΔP<0.05 vs. BM-MSCs. (B) HSC proliferation in the control and MSC-treated groups. *P<0.05 vs. control groups; ^ΔP<0.05 vs. BM-MSCs. (C) Apoptotic HSCs in the control and MSC-treated groups. BM-MSCs, bone marrow-derived mesenchymal stem cells; AD-MSCs, adipose tissue-derived mesenchymal stem cells; HSCs, hepatic stellate cells; α-SMA, α-smooth muscle actin. *P<0.05 vs. control; **P<0.05 vs. control, ^ΔP<0.05 vs. BM-MSCs.