Table I.
Levels of VEGF, IL-10, NGF and TGF-β1 secreted into the cell culture medium of HSCs co-cultured with BRLs, BM-MSCs or AD-MSCs.
Co-culture group | VEGF (pg/ml) | IL-10 (pg/ml) | NGF (pg/ml) | TGF-β1 (pg/ml) |
---|---|---|---|---|
BRLs | 21.08±5.15 | 17.91±3.16 | 10.13±1.52 | 53.27±12.68 |
BM-MSCs | 80.33±14.48a | 18.12±1.53 | 3.95±0.71a | 6.36±0.85a |
AD-MSCs | 78.52±15.79a | 17.37±1.92 | 7.46±0.54a,b | 8.79±0.93a,b |
Data are presented as the mean ± standard deviation.
P<0.05 vs. BRLs as the control
P<0.05 vs. BM-MSCs. VEGF, vascular endothelial growth factor; IL-10, interleukin-10; NGF, nerve growth factor; TGF-β1, transforming growth factor-β1; HSCs, hepatic stellate cells; BRL, buffalo rat liver cells; BM-MSCs, bone marrow-derived mesenchymal stem cells; AD-MSCs, adipose tissue-derived mesenchymal stem cells.