Figure 1.
Cardiac dilation in hearts from H/M-Sod2−/− mice. (A) Hearts from H/M-Sod2−/− mice demonstrated different parasternal long-axis M-mode echocardiographic images. (B) Hematoxylin & eosin staining showed marked dilation of dilated cardiomyopathy hearts from H/M-Sod2−/− mice compared with WT mice. (C) The myocardial sections from H/M-Sod2−/− mice indicated eccentric hypertrophy and myocardial disarray compared with hearts from WT mice. H/M-Sod2−/−, heart/muscle-specific manganese-superoxide dismutase-deficient mice; WT, wild type; PUFA, polyunsaturated fatty acids.