Table I.
Patient's characteristics | All patients (n=11) |
---|---|
Age (years), median (range) | 70.6±7.5 |
Gender | |
Male | 10 (90.9) |
Female | 1 (9.1) |
TTP, months | 3.9 (2.3–16.1) |
OS, months | 34.4 (5.9–51.7) |
Underlying cause | |
HBV | 2 (18.2) |
HCV | 6 (54.5) |
NBNC | 3 (27.3) |
ECOG performance score | |
0 | 10 (90.9) |
1 | 1 (9.1) |
Child-Pugh score | |
A | 11 (100.0) |
B | 0 (0.0) |
C | 0 (0.0) |
LCSGJ staging | |
II | 2 (18.2) |
III | 9 (91.8) |
AFP, ng/ml | 7.3 (3.5–188.0) |
DCP, mAU/ml | 24.0 (8.0–3589.0) |
Pretreatment HCC | |
Yes | 11 (100.0) |
No | 0 (0.0) |
Initial sorafenib dose, mg | |
800 | 9 (91.8) |
400 | 2 (18.2) |
Categorical data are expressed as n (%). Continuous data are expressed as mean ± standard deviation or median (range) by group. HBV, hepatitis B virus; HCV, hepatitis C virus; NBNC, HBV (−) and HCV (−); ECOG, Eastern Cooperative Oncology Group; LCSGJ, Liver Cancer Study Group of Japan; AFP, α-fetoprotein; DCP, des-γ-carboxy prothrombin; HCC, hepatocellular carcinoma. Child-Pugh score based on both clinical (ascites and encephalopathy) and laboratory (serum albumin, total bilirubin and prothrombin time) parameters.