Table III.

Drug-related, treatment-emergent adverse events.

AE	Grade 1 n=23	Grade 2 n=11	Grade 3 n=3	Total n (%)
Hand-foot skin reaction	7 (30.4)	3 (27.2)	0 (0.0)	10 (27.0)
Diarrhea	3 (13.0)	0 (0.0)	0 (0.0)	3 (8.1)
Alopecia	3 (13.0)	0 (0.0)	0 (0.0)	3 (8.1)
Pruritus	2 (8.7)	0 (0.0)	0 (0.0)	2 (5.4)
Hypertension	2 (8.7)	2 (18.2)	0 (0.0)	4 (10.8)
Hoarseness	2 (8.7)	0 (0.0)	0 (0.0)	2 (5.4)
Serum amylase increased	1 (4.3)	1 (9.0)	1 (33.3)	3 (8.1)
Platelet count decreased	1 (4.3)	1 (9.0)	1 (33.3)	3 (8.1)
Hepatobiliary disorders	1 (4.3)	1 (9.0)	0 (0.0)	2 (5.4)
Anorexia	1 (4.3)	0 (0.0)	0 (0.0)	1 (5.4)
White blood cell decreased	0 (0.0)	1 (9.0)	1 (33.3)	2 (5.4)
Blood bilirubin increased	0 (0.0)	1 (9.0)	0 (0.0)	1 (2.7)
Acute coronary syndrome	0 (0.0)	1 (9.0)	0 (0.0)	1 (2.7)

Categorical data are expressed as n (%). AE, adverse event.