Table III.
Univariate and multivariate analyses of overall survival.
| Multivariate analysis | |||
|---|---|---|---|
| Variable | Univariate analysis P-value | 95% CI | P-value |
| Age (≥65 years) | 0.456 | ||
| Sex (male) | 0.242 | ||
| HBs Ag (+) | 0.631 | ||
| HCV Ab (+) | 0.661 | ||
| Child-Pugh score (5) | 0.004 | 0.191–0.892 | 0.022 |
| AFP (≥1,000 ng/ml) | 0.169 | ||
| DCP (≥1,000 mAU/ml) | 0.452 | ||
| Previous treatment (present) | 0.457 | ||
| Maximum tumor size (≥100 mm) | 0.267 | ||
| Grade of portal vein invasion (Branch) | <0.001 | 0.118–0.614 | 0.002 |
| Hepatic vein invasion (present) | 0.176 | ||
| Regimen (NFP) | 0.015 | ||
| Therapeutic effect (CR or PR) | <0.001 | 0.220–0·752 | 0.009 |
CI, confidence interval; HB, hepatitis B; HCV, hepatitis C virus; AFP, α-fetoprotein; DCP, des-γ-carboxy prothrombin; NFP, new 5-fluorouracil and cisplatin therapy; CR, complete response; PR, partial response.