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. 2017 Dec 21;48:89. doi: 10.1186/s13567-017-0494-6

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Diagrams of chromosomal mutation, plasmid maps and phenotypic feature of the sopB mutant in Salmonella Choleraesuis strains. A Chromosomal map of ΔsopB deletion mutation. B Empty plasmid vector pYA3493 and expression vector pS-SaoA. C Histopathological observations of rabbit ileal loops injected with different Salmonella Choleraesuis strains or LB control for 8 h. Bar: 50 μm. The small square showed the neutrophils in the submucosa of rabbit ileal injected with wild-type C78-3 strain. D Fluid secretion induced by Salmonella Choleraesuis strains in rabbit ileal loops. a, P < 0.05, wildtype Salmonella Choleraesuis C78-3 compared with LB, rSC0017, rSC0018(pS-SaoA), rSC0016(pS-SaoA) and rSC0011(pS-SaoA); b, P < 0.05, Salmonella Choleraesuis with ΔsopB mutation rS0017 compared to LB, rSC0018(pS-SaoA), rSC0011(pS-SaoA) and rSC0016(pS-SaoA); *P < 0.05, for the indicated strains were compared each other.