Table 5.
Comparison of adverse events between the five kinds of antipsychotics after 6–8 weeks of treatment
| Groups | N | EPS | Abnormal ECG | Abnormal liver function | Constipation | Leukopenia |
|---|---|---|---|---|---|---|
| Aripiprazole | 15 | 6 | 4 | 5 | 1 | 0 |
| Risperidone | 20 | 6 | 4 | 6 | 2 | 0 |
| Quetiapine | 23 | 3 | 8 | 7 | 3 | 4 |
| Olanzapine | 21 | 1 | 8 | 5 | 1 | 2 |
| Ziprasidone | 5 | 3 | 3 | 1 | 0 | 0 |
| χ 2 | 12.23 | 3.75 | 0.64 | 1.60 | 6.899 | |
| P value | < 0.05 | > 0.05 | > 0.05 | > 0.05 | > 0.05 |
Abnormal liver function: this mainly included elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST). ECG: electrocardiogram. Including S-T and T wave change, and prolongation of corrected Q-T interval
N: number of patients; EPS: extrapyramidal symptoms, including akathisia, acute dystonia, and parkinsonian syndromes