TABLE 5.
Antibiotic and biocide susceptibility of M. ulceransa
| Drug (generic name) | Range | MIC50 | MIC90 |
|---|---|---|---|
| Rifampin | 0.12 to 4.0 | 0.5 | 2.0 |
| Streptomycin | 0.12 to 1.0 | 0.25 | 0.5 |
| Amikacin | 0.25 to 2.0 | 0.5 | 2.0 |
| Moxifloxacin | 0.015 to 0.5 | 0.12 | 0.5 |
| R207910 (bedaquiline) | 0.015 to 0.12 | 0.03 | 0.06 |
| Linezolid | 0.25 to 4.0 | 0.5 | 2.0 |
| PA-824 (pretomanid) | 4.0 to 16 | 16 | >16 |
| Saprofloxacin | 0.1 to 2 | ND | 0.5 |
| Ofloxacin | 0.1 to 2 | ND | 2 |
| Ciprofloxacin | 0.1 to 2 | ND | 1 |
| Clarithromycin | 0.125 to 4 | ND | 0.125 to 2 |
| Clofazimine | 0.06 to 2 | ND | 0.25 to 0.5 |
| Ivermectin | 0.125 to 64 | ND | >64 |
| Milbemycin oxime | 0.125 to 64 | ND | 1 to 8 |
| Moxidectin | 0.125 to 64 | ND | 16 to >64 |
| Selamectin | 0.125 to 64 | ND | 1 to 4 |
| Abamectin | 0.125 to 64 | ND | >64 |
| Doramectin | 0.125 to 64 | ND | >64 |
| Emamectin | 0.125 to 64 | ND | 16 to 32 |
| Eprinomectin | 0.125 to 64 | ND | >64 |
a
MICs are given in grams per liter. ND, not determined.