Table 5.
Unadjusted and Adjusted Odds Ratios Disease Progression in the FLU003 Inpatient Cohort by Influenza Virus Type/Influenza A Virus Subtype
A(H3N2) vs A(H1N1)pdm09 | B vs A(H1N1)pdm09 | A(H3N2) vs B | |||||||
---|---|---|---|---|---|---|---|---|---|
Enrolled From General Ward | OR | 95% CI | P Value | OR | 95% CI | P Value | OR | 95% CI | P Value |
Unadjusteda | 0.74 | 0.48–1.15 | .18 | 0.82 | 0.47–1.45 | .50 | 0.90 | 0.50–1.62 | .73 |
Adjustedb | 0.79 | 0.44–1.43 | .43 | 0.95 | 0.49–1.84 | .89 | 0.83 | 0.43–1.59 | .57 |
Enrolled from ICU | |||||||||
Unadjusteda | 0.81 | 0.43–1.52 | .51 | 0.87 | 0.34–2.26 | .78 | 0.93 | 0.33–2.57 | .88 |
Adjustedb | 0.11 | 0.38–3.25 | .85 | 1.06 | 0.30–3.83 | .92 | 1.05 | 0.25–4.45 | .95 |
Total | |||||||||
Unadjusteda | 0.76 | 0.53–1.09 | .14 | 0.84 | 0.52–1.36 | .48 | 0.91 | 0.55–1.51 | .71 |
Adjustedb | 0.87 | 0.52–1.44 | .59 | 1.00 | 0.57–1.75 | 1.00 | 0.87 | 0.48–1.56 | .64 |
Abbreviations: CI, confidence interval; ICU, intensive care unit; OR, odds ratio.
aOverall is stratified by hospital unit at enrollment.
bStratified by hospital unit at enrollment and adjusted for region, age, gender, ethnicity, body mass index, smoking, duration of symptoms, ≥1 comorbidities, ≥1 severe complications, influenza vaccine in past year, and use of antivirals on or before enrollment date.