Fig. 11.
ML213-induced hyperpolarization is reversed by KV7 channel inhibition with XE991. (A) A representative current-clamp recording from a freshly isolated DSM cell illustrating hyperpolarization of the DSM cell membrane potential by ML213 (10 µM) and that the ML213-induced hyperpolarization is reversed by the KV7 channel inhibitor XE991 (10 µM). (B) Summary data for the hyperpolarizing effects of ML213 (10 µM) on the DSM cell membrane potential (n = 7, N = 5, *P < 0.05) effects reversible by 10 µM XE991 (n = 7, N = 5; #P < 0.05; two-tailed paired Student’s t-test). See Supplemental Fig. 11 for display of summary data as scatterplots with means.