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. 2017 Oct 23;67(1):146–154. doi: 10.2337/db17-0802

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© 2017 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

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ORs and 95% CIs for decreased risk of IA associated with 25(OH)D concentration (5 nmol/L increase) and being vitamin D sufficient (≥50 nmol/L) versus insufficient by number of minor alleles (the C allele) at rs7975232 in the vitamin D receptor gene. Analyses are adjusted for HLA-DR3/4 and the first two PCs indicating ancestry; and ORs are calculated from the SNP × vitamin D measure interaction terms. For childhood vitamin D measures, we analyzed 376 case subjects and their control subjects (297 case subjects with 3 control subjects, 71 case subjects with 2 control subjects, and 8 case subjects with 1 control subject) with complete plasma 25(OH)D and vitamin D genetic data. For the early infancy vitamin D measures, we analyzed 360 case subjects and their control subjects (269 case subjects with 3 control subjects, 83 case subjects with 2 control subjects, and 8 case subjects with 1 control subject).