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Age-related changes in oral glucose tolerance and insulin levels in βPKD1KO and control mice. Blood glucose (A–C) and plasma insulin (D–F) in mice during OGTT at week 0 (A and D) and after 8 (B and E) and 12 (C and F) weeks on normal diet. Data are mean ± SEM of 5–10 animals per group. *P < 0.05 compared with WT after two-way ANOVA with Dunnett post hoc adjustment for multiple comparisons.
