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. 2017 Oct 7;10(5):444–457. doi: 10.1159/000478094

Table 1.

Obesity predisposing SNPs selected for the study

SNP Gene
Described association
Reference
name abbreviation odds ratio of obesity mean difference in BMI (β)
rs1137101 leptin receptor LEPR 1.13 Paracchini et al. [26]

rs2815752 neuronal growth regulator NEGR1 0.13 Speliotes et al. [27]

rs2867125 transmembrane protein 18 TMEM18 0.31 Speliotes et al. [27]
rs6548238 0.26 Willer et al. [28]

rs1801282 peroxisome proliferator-activated receptor gamma PPARG 0.06 Galbete et al. [29]

rs2241766 adiponectin, C1Q and ADIPOQ 1.39 Wu et al. [30]
rs1501299 collagen domain containing 0.89 Lu et al. [31]

rs10938397 glucosamine-6-phosphate deaminase 2 GNPDA2 0.18 Speliotes et al. [27]

rs16139 neuropeptide Y NPY 0.58 Yeung et al. [32]
rs925946 brain-derived neurotrophic BDNF 1.11 Thorleifsson et al. [33]
rs6265 factor 1.12 Thorleifsson et al. [33]

rs660339 uncoupling protein 2 UCP2 0.39 Brondani et al. [34]
rs659366 (mitochondrial, proton carrier) 1.06 Brondani et al. [34]

rs6499640 fat mass and obesity- FTO 1.16 Thorleifsson et al. [33]
rs1558902 associated protein 0.39 Speliotes et al. [27]
rs1121980 0.31 Vimaleswaran et al. [35]
rs9939609 0.33 Willer et al. [28]
rs9941349 0.56 Cronin et al. [36]

rs17782313 melanocortin 4 receptor MC4R 0.2 Willer et al. [28]
rs12970134 1.12 Thorleifsson et al. [30]