Table 1.
SNP | Gene |
Described association |
Reference | ||
---|---|---|---|---|---|
name | abbreviation | odds ratio of obesity | mean difference in BMI (β) | ||
rs1137101 | leptin receptor | LEPR | 1.13 | – | Paracchini et al. [26] |
rs2815752 | neuronal growth regulator | NEGR1 | – | 0.13 | Speliotes et al. [27] |
rs2867125 | transmembrane protein 18 | TMEM18 | – | 0.31 | Speliotes et al. [27] |
rs6548238 | – | 0.26 | Willer et al. [28] | ||
rs1801282 | peroxisome proliferator-activated receptor gamma | PPARG | – | 0.06 | Galbete et al. [29] |
rs2241766 | adiponectin, C1Q and | ADIPOQ | 1.39 | – | Wu et al. [30] |
rs1501299 | collagen domain containing | 0.89 | – | Lu et al. [31] | |
rs10938397 | glucosamine-6-phosphate deaminase 2 | GNPDA2 | – | 0.18 | Speliotes et al. [27] |
rs16139 | neuropeptide Y | NPY | – | 0.58 | Yeung et al. [32] |
rs925946 | brain-derived neurotrophic | BDNF | 1.11 | – | Thorleifsson et al. [33] |
rs6265 | factor | 1.12 | – | Thorleifsson et al. [33] | |
rs660339 | uncoupling protein 2 | UCP2 | – | 0.39 | Brondani et al. [34] |
rs659366 | (mitochondrial, proton carrier) | 1.06 | Brondani et al. [34] | ||
rs6499640 | fat mass and obesity- | FTO | 1.16 | – | Thorleifsson et al. [33] |
rs1558902 | associated protein | – | 0.39 | Speliotes et al. [27] | |
rs1121980 | – | 0.31 | Vimaleswaran et al. [35] | ||
rs9939609 | – | 0.33 | Willer et al. [28] | ||
rs9941349 | – | 0.56 | Cronin et al. [36] | ||
rs17782313 | melanocortin 4 receptor | MC4R | – | 0.2 | Willer et al. [28] |
rs12970134 | 1.12 | – | Thorleifsson et al. [30] |