Table 3. Adjusted odds ratio (95% CI) for dyslipidemia and lipid parameters by sex-specific quartiles of serum ferritin.
| Men (3522) | P value | Women (3587) | P value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | Q1 | Q2 | Q3 | Q4 | |||
| Ferritin (mg/L) | 56.42 (23.92) | 100.06 (22.14) | 154.27 (39.58) | 379.90 (323.36) | 24.52 (9.39) | 47.12 (12.39) | 77.99 (20.83) | 156.40 (109.31) | ||
| Dyslipidemia | ||||||||||
| Model 1a | 1 | 1.12(0.93–1.36) | 1.59(1.32–1.93) | 2.75(2.25–3.37) | <0.001 | 1 | 1.56(1.29–1.88) | 2.64(2.16–3.23) | 4.24(3.40–5.28) | <0.001 |
| Model 2b | 1 | 1.06(0.86–1.29) | 1.41(1.15–1.73) | 2.12(1.70–2.64) | <0.001 | 1 | 1.35(1.10–1.66) | 1.79(1.43–2.24) | 2.23(1.73–2.89) | <0.001 |
| Model 3c | 1 | 1.05(0.86–1.29) | 1.37(1.12–1.69) | 2.02(1.62–2.52) | <0.001 | 1 | 1.36(1.11–1.67) | 1.84(1.46–2.31) | 2.14(1.64–2.78) | <0.001 |
| TG | ||||||||||
| Model 1 | 1 | 1.40(1.12–1.75) | 2.13(1.72–2.63) | 3.68(2.99–4.52) | <0.001 | 1 | 1.51(1.19–1.90) | 2.19(1.75–2.74) | 4.02(3.24–4.99) | <0.001 |
| Model 2 | 1 | 1.30(1.03–1.64) | 1.88(1.50–2.35) | 2.86(2.30–3.56) | <0.001 | 1 | 1.32(1.04–1.69) | 1.59(1.24–2.03) | 2.47(1.92–3.17) | <0.001 |
| Model 3 | 1 | 1.27(1.00–1.60) | 1.82(1.45–2.28) | 2.66(2.13–3.32) | <0.001 | 1 | 1.32(1.03–1.69) | 1.59(1.24–2.04) | 2.37(1.84–3.06) | <0.001 |
| TC | ||||||||||
| Model 1 | 1 | 1.01(0.82–1.25) | 1.43(1.17–1.74) | 2.07(1.70–2.52) | <0.001 | 1 | 1.50(1.22–1.84) | 2.77(2.27–3.39) | 3.67(3.01–4.47) | <0.001 |
| Model 2 | 1 | 0.98(0.79–1.21) | 1.34(1.09–1.66) | 1.77(1.44–2.17) | <0.001 | 1 | 1.17(0.94–1.46) | 1.63(1.31–2.03) | 1.68(1.34–2.11) | <0.001 |
| Model 3 | 1 | 0.96(0.77–1.19) | 1.31(1.06–1.62) | 1.67(1.35–2.06) | <0.001 | 1 | 1.18(0.95–1.47) | 1.65(1.33–2.06) | 1.66(1.32–2.08) | <0.001 |
| HDL-C | ||||||||||
| Model 1 | 1 | 0.86(0.72–1.02) | 0.74(0.63–0.88) | 0.54(0.45–0.64) | <0.001 | 1 | 0.91(0.77–1.08) | 0.93(0.78–1.10) | 0.72(0.60–0.85) | 0.001 |
| Model 2 | 1 | 0.91(0.76–1.08) | 0.88(0.73–1.05) | 0.70(0.59–0.85) | 0.002 | 1 | 0.88(0.74–1.05) | 0.91(0.76–1.09) | 0.72(0.59–0.88) | 0.005 |
| Model 3 | 1 | 0.91(0.76–1.09) | 0.87(0.73–1.04) | 0.70(0.58–0.85) | 0.002 | 1 | 0.89(0.74–1.06) | 0.90(0.75–1.09) | 0.72(0.59–0.89) | 0.016 |
| LDL-C | ||||||||||
| Model 1 | 1 | 0.86(0.69–1.07) | 1.11(0.90–1.37) | 1.37(1.12–1.68) | <0.001 | 1 | 1.67(1.34–2.08) | 3.23(2.62–3.99) | 3.63(2.94–4.48) | <0.001 |
| Model 2 | 1 | 0.85(0.68–1.06) | 1.08(0.87–1.33) | 1.21(0.97–1.49) | 0.014 | 1 | 1.30(1.03–1.63) | 2.00(1.59–2.51) | 1.72(1.36–2.51) | <0.001 |
| Model 3 | 1 | 0.84(0.68–1.05) | 1.06(0.86–1.32) | 1.17(0.94–1.45) | 0.031 | 1 | 1.30(1.03–1.65) | 2.02(1.60–2.54) | 1.69(1.32–2.15) | <0.001 |
TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol;
a: Model 1, ORs without adjustment;
b Model 2, ORs adjusted for Model 1 plus age, BMI, smoking status, alcohol consumption, education level, systolic and diastolic blood pressure, CRP levels, daily Carbohydrate, fat, energy and protein intake.
c Model 3, ORs adjusted for Model 2 plus history of diabetes and HOMA-IR.