Comparison of MPI liver imaging using custom MPI LNA, CLC1002 op amp, and SR560 preamplifier. (a) Coregistered MPI and X-ray image of intravenous injections of SPIO tracer in rat, imaged using custom MPI LNA. (b) The custom LNA achieves significantly improved SNR performance compared to commercial amplifiers. MPI Imaging: 4 × 4 × 10 cm FOV, 7.6-min total acquisition. X-ray Imaging: three stitched FOVs, 30 kV, 800 μA, 10-s acquisition each.