Table 2: Characteristics of patients with renal cell carcinoma treated with radical or partial nephrectomy.
| Characteristic | Cancer stage; no. (%) of patients* | |||
|---|---|---|---|---|
| All patients n = 1982 |
pT1n = 1380 | pT2n = 164 | pT3 n = 438 |
|
| Age at procedure, yr | ||||
| Mean (95% CI) | 60.3 (59.7-60.8) | 59.5 (58.9-60.1) | 58.4 (58.9-60.4) | 63.2 (62.1-64.2) |
| Median (IQR) | 60.7 (52.5-68.4) | 60.2 (52.0-68.0) | 59.4 (49.5-67.5) | 63.1 (55.8-71.0) |
| Age > 75 yr at procedure | 198 (10.0) | 116 (8.4) | 17 (10.4) | 66 (15.1) |
| Male sex | 1314 (66.3) | 883 (64.0) | 112 (68.3) | 319 (72.8) |
| High grade (n = 1830)† | 866 (43.7) | 458 (33.2) | 85 (51.8) | 318 (72.6) |
| Radical nephrectomy | 846 (42.7) | 356 (25.8) | 140 (85.4) | 351 (80.1) |
| Positive surgical margin (n = 1935) | 129 (6.5) | 65 (4.7) | 1 (0.6) | 64 (14.6) |
| Histologic type‡ | ||||
| Clear cell renal cell carcinoma | 1413 (71.3) | 949 (68.8) | 97 (59.1) | 368 (84.0) |
| Papillary renal cell carcinoma | 325 (16.4) | 254 (18.4) | 35 (21.3) | 35 (8.0) |
| Chromophobe renal cell carcinoma | 155 (7.8) | 115 (8.3) | 24 (14.6) | 16 (3.6) |
| Renal cell carcinoma, unspecified | 89 (4.5) | 62 (4.5) | 8 (4.9) | 19 (4.3) |
| Computed tomography§ | 1048 (52.9) | 640 (46.4) | 95 (57.9) | 314 (71.7) |
| Intra- or postoperative medical complication(s) | 291 (14.7) | 195 (14.1) | 25 (15.2) | 72 (16.4) |
| Family history of renal cell carcinoma | 111 (5.6) | 79 (5.7) | 7 (4.3) | 25 (5.7) |
| Status (n = 1639)¶ | ||||
| Alive with disease | 161 (8.1) | 68 (4.9) | 20 (12.2) | 73 (16.7) |
| No evidence of disease | 1655 (83.5) | 1227 (88.9) | 128 (78.0) | 300 (68.5) |
| Overall death | 81 (4.1) | 22 (1.6) | 13 (7.9) | 46 (10.5) |
| Lost to follow-up | 81 (4.1) | 61 (4.4) | 3 (1.8) | 17 (3.9) |
| Unknown | 4 (0.2) | 2 (0.1) | 0 (0.0) | 2 (0.4) |
Note: CI = confidence interval, IQR = interquartile range.
*Except where noted otherwise.
†Fuhrman grade 3 (moderately to poorly differentiated tumour cells) or 4 (poorly differentiated tumour cells).
‡Primary histologic type from pathology report.
§Patient received at least 1 computed tomography examination of the chest or abdomen during surveillance after nephrectomy.
¶At last follow-up visit for kidney cancer.