Table 4. ROC Threshold Analysis for LA Strain in Validation Group Using 2009 DD Guidelines.
| Derivation Group | Validation Group | ||||||
|---|---|---|---|---|---|---|---|
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| AUC | Optimal Cutoff | Sensitivity | Specificity | PPV | NPV | Accuracy | |
| Grade 0 vs. grade 1–3 | 0.86 | 35% | 90 | 59 | 61 | 90 | 72 |
| Grade 0–1 vs. grade 2–3 | 0.89 | 24% | 75 | 92 | 75 | 92 | 88 |
| Grade 0–2 vs. grade 3 | 0.91 | 19% | 90 | 95 | 64 | 99 | 95 |
AUC = area under the curve; DD = diastolic dysfunction; LA = left atrial; NPV = negative predictive value; PPV = positive predictive value; ROC = receiver-operating characteristic.