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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: J Cell Physiol. 2017 Nov 24;233(4):3540–3551. doi: 10.1002/jcp.26211

Figure 2.

Figure 2

TIEG regulation of the SOST promoter. A). Identification of putative TIEG binding sites in the proximal promoter of the mouse SOST gene. B). Luciferase assays indicating activity of the SOST promoter following transfection into U2OS cells in the presence and absence of a TIEG expression construct. Depiction (C) and luciferase activity (D) of SOST promoter deletion constructs in U2OS cells in the presence and absence of a TIEG expression construct. E). Transient ChIP-PCR analysis indicating TIEG association with indicated SOST promoter constructs. * Denotes significance at the P<0.05 level between controls and indicated conditions.