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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: J Cell Physiol. 2017 Sep 12;233(4):2671–2680. doi: 10.1002/jcp.26148

Figure 1.

Figure 1

A) X-rays of littermate male Hdac3fl/fl:Osx1-Cre− and Hdac3fl/fl:Osx1-Cre+ mice at 26 weeks of age, after having been fed a high-fat diet between 4 weeks to 26 weeks of age. Leaner body mass and lack of hepatic hypertrophy are notable the Hdac3fl/fl:Osx1-Cre+ animals. B) X-rays of littermate male control (Hdac3fl/fl:Osx1-Cre−) and Hdac3Osx CKO (Hdac3fl/fl:Osx1-Cre+) mice at 8 weeks of age, after having been fed a high-fat diet between 4 and 8 weeks of age. Leaner body mass is notable. C) X-rays of littermate male control (Hdac3fl/fl:OCN-Cre−) and Hdac3OCN CKO (Hdac3fl/fl:OCN-Cre+) mice at 8 weeks of age, after having been fed a high-fat diet between 4 and 8 weeks of age. Body mass is comparable between genotypes. D) Body composition in Hdac3Osx CKO as compared to control littermates; *p<0.05 vs. control. E) Body composition is not different between Hdac3OCN CKO and control littermates.