Table 3.
Patient fMRI responses to hand squeeze and tennis motor imagery.
| ID | LoC at fMRI | Hand squeezing | Tennis playing |
|---|---|---|---|
| P1a | Coma | − | − |
| P2a | MCS+ | + | − |
| P3a | UWS | + | − |
| P4a | MCS− | − | + |
| P5a | MCS+ | + | − |
| P6 | MCS+ | − | − |
| P7 | UWS | − | + |
| P8 | UWS | − | − |
| P9 | MCS− | − | − |
| P10 | UWS | − | − |
| Total percent (95% exact CI) | 30% (6.7–65.3) | 20% (2.5–55.6) | |
| Sensitivity (95% exact CI) | 66.7% (12.5–98.2) | 0% (0–70.8) | |
| Specificity (95% exact CI) | 85.7% (42.1–99.6) | 71.4% (29.0–96.3) | |
| Accuracy | 80% | 50% |
Sensitivity, specificity, and accuracy of motor imagery paradigm detection of command following in patients who demonstrated behavioral evidence of command following.
fMRI, functional magnetic resonance imaging; LoC, level of consciousness; MCS−, minimally conscious state without language; MCS+, minimally conscious state with language; UWS, unresponsive wakefulness syndrome; CI, confidence interval.
aThe patient was receiving sedatives at the time of data acquisition (see Table S3 in Supplementary Material for details). Image acquisition parameters for P10 differed from those of the other subjects (see Materials and Methods for details).