Table 7.

Health Technology Assessment in considered CEE countries.

Aspect required	Bulgaria	Croatia	Czechia	Estonia	Hungary	Latvia	Lithuania	Poland	Romania	Slovakia
Is HTA dossier obligatory in pricing and reimbursement submission?	Yes	No but alternative assessment has to be submitted	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
In case if HTA is not obligatory it could be submitted with a reimbursement application as a additional facultative dossier?	It's obligatory	Yes	It's obligatory	It's obligatory	It's obligatory	It's obligatory	It's obligatory	It's obligatory	It's obligatory	It's obligatory
Are HTA guidelines obligatory for submitted HTA dossier attached to the reimbursement application?	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
What institutions are responsible for determining “benefit” and “value” of pharmaceuticals?	HTA Commission National Council Ministry of Health	The CHIF and their Expert council of the CHIF	State Institute for Drug Control (SUKL)	Ministry of Social Affairs Health Insurance Fund	The National Institute of Health Insurance Fund Management (since 2016) The HTA Office at the National Institute of Pharmacy and Nutrition The Medical Professional Colleges The Technology Assessment Committee	The National Health Service of Latvia	Ministry of Health The State Medicines Control Agency National Health Insurance Fund under the Ministry of Health	Polish HTA Agency (Agency for Health Technology Assessment and Tariff Systems; AOTMiT)	National Agency for Medicines and Medical Devices in Romania	Slovak Ministry of Health The Reimbursement Committee