Table 1.
Genes with altered expression when whiB1 was underexpressed
| Gene | Rv number | Fold change | Function | Operon |
|---|---|---|---|---|
| espD | Rv3614c | 20.9 | ESX-1 secretion-associated protein EspD | espA-E |
| espC | Rv3615c | 19.8 | ESX-1 secretion-associated protein EspC | espA-E |
| espA | Rv3616c | 13.1 | ESX-1 secretion-associated protein EspA | espA-E |
| Rv3613c | Rv3613c | 11.5 | Hypothetical protein | espA-E |
| Rv2660c | Rv2660c | 6.1 | Hypothetical protein | Rv2660c |
| Rv3662c | Rv3662c | 5.8 | Hypothetical protein | Rv3662c |
| papA1 | Rv3824c | 5.3 | Acyltransferase | pks2-papA1-mmpL8 |
| mftE | Rv0695 | 5.2 | Mycofactocin system creatinine amidohydrolase family protein | mftEF |
| mmpL8 | Rv3823c | 5.0 | Integral membrane transport protein MmpL8 | pks2-papA1-mmpL8 |
| mftF | Rv0696 | 4.7 | Mycofactocin biosynthesis glycosyltransferase | mftEF |
| Rv3612c | Rv3612c | 4.5 | Hypothetical protein | espA-E |
| ppsE | Rv2935 | 4.4 | Phthiocerol synthesis polyketide synthase type I | ppsE |
| Rv0755A | Rv0755A | 4.2 | Transposase | Rv0755A |
| Rv2159c | Rv2159c | 4.1 | Hypothetical protein | Rv2159c |
| Rv1638A | Rv1638A | 4.1 | Hypothetical protein | Rv1639c-Rv1638A |
| lipX | Rv1169c | 4.1 | Lipase | lipX |
| Rv1986 | Rv1986 | 4.1 | Amino acid transporter | Rv1986 |
| Rv3572 | Rv3572 | 4.0 | Hypothetical protein | Rv3572 |
| pks2 | Rv3825c | 3.8 | Phthioceranic/hydroxyphthioceranic acid synthase | pks2-papA1-mmpL8 |
| tgs2 | Rv3734c | 3.5 | Diacyglycerol O-acyltransferase | tgs2 |
| Rv2632c | Rv2632c | 3.5 | Hypothetical protein | Rv2633c-Rv2632c |
| Rv1639c | Rv1639c | 3.4 | Hypothetical protein | Rv1639c-Rv1638A |
| Rv0108c | Rv0108c | 3.3 | Hypothetical protein | Rv0108c |
| lat | Rv3290c | 3.3 | L-lysine-epsilon aminotransferase | lat |
| Rv0888 | Rv0888 | 3.3 | Hypothetical protein | Rv0888 |
| pks3 | Rv1180 | 3.3 | Polyketide beta-ketoacyl synthase | pks3 |
| Rv2633c | Rv2633c | 3.2 | Hypothetical protein | Rv2633c-Rv2632c |
| Rv2459 | Rv2459 | 3.2 | MFS-type transporter | Rv2459 |
| lipQ | Rv2485c | 3.1 | Carboxylesterase LipQ | lipQ |
| Rv3633 | Rv3633 | 3.0 | Hypothetical protein | Rv3633 |
| Rv1393c | Rv1393c | 3.0 | Monoxygenase | Rv1393c |
| mbtJ | Rv2385 | 0.3 | Acetyl hydrolase | mbtJ |
| cyp121 | Rv2276 | 0.3 | Cytochrome P450 | cyp121 |
| mbtI | Rv2386c | 0.3 | Salicylate synthase | mbtI |