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. 2017 Dec 18;10:422. doi: 10.3389/fnmol.2017.00422

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Copyright © 2017 Zhou, Zong, Zhang, Zhang, Zhang, Wu and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of PNU-282987 on NR2B expression levels in the retina. (A) Immunoblot analysis of NR2B in the retinas of control and glaucomatous rats before and after PNU-282987 injection. Full-length blots are presented in Supplementary Figure S1. (B) Quantitative analysis of NR2B expression. (C) Confocal images showing the distribution of NR2B labeled in the GCL (arrow) and INL (arrow) in the normal, glaucoma and glaucoma + PNU-282987 conditions. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer. Scale bar: 30 μm. The data are presented as the mean ± standard error of five samples for each experiment. *p < 0.05 (one-way analysis of variance).