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. 2017 Dec 22;7:18073. doi: 10.1038/s41598-017-18287-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Role of the different cell types in the postnatal synaptogenesis. (a) Counts and Bonferroni corrected p-values of the enrichments of markers in the synaptogenesis cluster C6. Cornu Ammonis (CA) pyramidal neurons and SomatoSensory (SS) pyramidal neurons are pooled under the label “pyramidal neurons.” (b) Identifying the roles of specialized cells in the postnatal synaptogenesis. The heatmap exemplifies the contributions of each of the 11 major hippocampal cell types to the biological functions that were attributed to C6 by standard GO. A red colored cell means that the genes annotated with that certain function (row) mostly belong to that specific cell type (column). Details for some interesting GO terms are shown to the right: lists of cell type markers belonging to C6 and contributing to (adult) neurogenesis, adult behavior and (adult) regulation of blood circulation. Bars represent the expression in the 5 developmental stages (mean +/− SEM).