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. 2017 Dec 22;8:38. doi: 10.1186/s13293-017-0159-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Study design of an approach to identify sex differences of phenotypical traits in thyroid diseases. Aging study was performed to characterize natural sex differences in different life stages between male and female mice in euthyroid, hyperthyroid and hypothyroid conditions [13]