Fig. 3.

Body weight change of adult and old mice of both sexes in eu-, hyper- and hypothyroid conditions. BW was related to individual start weight in adult (a–c) and old (d–f) male and female mice. Sex differences in euthyroid (a, d), hyperthyroid (b, e) and hypothyroid (c, f) conditions were assessed. TH excess resulted in BW gain of females, while males lost BW in both ages. No sex difference was observed under TH deprivation. Data are presented as mean ± SD, n = 7–11 animals/sex/treatment, two-way ANOVA followed by Bonferroni post hoc analysis, *p < 0.05, **p < 0.01, ***p < 0.001