Table 1.
Body weight of adult and old, male and female mice at first (start) and last (final) day of experiment
| Age | Sex | Start [g] | Final eu [g] | Final hyper [g] | Final hypo [g] |
|---|---|---|---|---|---|
| Adult | Males | 40.2 ± 5.0 | 45.8 ± 3.7 ** | 40.1 ± 4.1 | 35.6 ± 2.0 * |
| Females | 28.0 ± 1.4†††† | 30.5 ± 3.1†† | 34.3 ± 2.2 *** | 27.0 ± 1.6 | |
| Old | Males | 39.0 ± 5.2 | 41.3 ± 3.7 | 36.9 ± 5.3 | 34.0 ± 3.1 * |
| Females | 30.3 ± 3.5†††† | 32.8 ± 3.2†††† | 33.7 ± 4.4† | 28.7 ± 1.7†††† |
Data are presented as mean ± SD, n = 7–11 animals/sex/treatment, two-way ANOVA followed by Bonferroni post hoc analysis, *p < 0.05, **p < 0.01, ***p < 0.001 multiple comparison to start weight of each sex, † p < 0.05, †† p < 0.01, †††† p < 0.001 for sex difference at respective thyroid status. F (3,84) = 16.07, p < 0.0001 for treatment effect in adult, F (3,96) = 6.705, p = 0.0004 for treatment effect in old mice. F (1,84) = 181.6, p < 0.0001 for sex effect in adult, F (1,96) = 48.68, p < 0.0001 for sex effect in old mice and F (3,84) = 7.122, p = 0.0003 for interaction in adult, F (3,96) = 2.078, p = 0.1082 for interaction in old mice