Table S2.
Search strategy for Cochrane database
| Query | Facet | Hits | |
|---|---|---|---|
| 1 | MeSH descriptor: [Pain] explode all trees | Emergency and trauma-associated pain | 33,832 |
| 2 | pain* or agony or agoniz* or nocicept* or sur* near/3 pain or proced* near/3 pain | 93,700 | |
| 3 | #1 or #2 | 99,555 | |
| 4 | MeSH descriptor: [Wounds and Injuries] explode all trees | 16,427 | |
| 5 | wound* or injur* or traum* or casualt* or fracture* or laceration* or burn* or dislocation* or contusion* | 73,688 | |
| 6 | MeSH descriptor: [Emergencies] explode all trees | 662 | |
| 7 | pre near/3 hospital* or pre?hospital or prehospital | 1,277 | |
| 8 | emergenc* | 19,137 | |
| 9 | #4 or #5 or #6 or #7 or #8 | 90,705 | |
| 10 | #3 and #9 | 18,620 | |
| 11 | MeSH descriptor: [Ambulances] this term only | 107 | |
| 12 | paramed* | 780 | |
| 13 | #11 or #12 | 861 | |
| 14 | pain near/3 “treatment” or pain near/3 “management” | 11,915 | |
| 15 | #13 and #14 | 31 | |
| 16 | #10 or #15 | 18,629 | |
| 17 | methoxyflurane or “da 759” or da759 or inhalan or “methoxy flurane” or methoxyfluorane or methoxyfluran or metofan or metofane or “nsc 110432” or nsc110432 or penthrane or pentrane or penthrox or penthrox:ab,ti | Intervention | 71 |
| 18 | paracetamol or “paracetamol”:ab,ti | 4,414 | |
| 19 | nitrous oxide or “nitrous oxide”:ab,ti or nitrous next/2 oxide or n2o | 5,013 | |
| 20 | #17 or #18 or #19 | 9,312 | |
| 21 | #16 and #20 | Combined | 1,139 |
| 22 | #16 and #20 in Trials | 744 | |
| 23 | Trials pertaining to Penthrox and nitrous oxide for screening | 180 |