Table 4.
Chr | Locus | Gene | Missing | Minor Allele | MAF | P |
---|---|---|---|---|---|---|
3 | rs1732170 | GSK3β | 0 | T | .402 | .466 |
5 | rs6295 | HTR1A | 2 | C | .497 | .878 |
6 | rs13212041 | HTR1B | 34 | C | .216 | .914 |
6 | rs1799971 | OPRM1 | 0 | G | .127 | .957 |
11 | rs6265 | BDNF | 0 | T | .200 | .487 |
11 | rs1800497 | ANKK1 | 0 | A | .183 | .875 |
12 | rs2228570 | VDR | 0 | A | .414 | .475 |
13 | rs63131 | HTR2A | 0 | A | .419 | .002 |
13 | rs63111 | HTR2A | 7 | T | .418 | .003 |
14 | rs11624704 | NRXN3 | 0 | C | .150 | .754 |
22 | rs4680 | COMT | 0 | G | .482 | .780 |
5 | rs3814424c | LINC00461 | 15 | T | .170 | .229 |
8 | rs6981523n | XKR6 | 7 | C | .460 | .542 |
22 | rs9611519n | L3MBTL2/CHADL | 1 | T | .271 | .995 |
Note.
loci are in high LD (i.e., r2 = .996). Bolding of loci indicates significant effects were identified. Follow-up univariate analyses were only conducted for loci with significant multivariate effects.
previously associated with Conscientiousness and Neuroticism, respectively, in recent GWAS (Lo et al., 2016).