Fig. 2. Grainyhead-like 2 inversely correlates with MIR122 expression in human livers.
Pri-MIR122 expression in (A)human livers (n=10–12/group) and (B)alcohol-fed WT murine livers (n=7–8/group) and hepatocytes (n=5/group). ChIP-qPCR of the GRHL binding results presented as % input of (C)GRHL2 and respective IgG controls. (D)GRHL2 mRNA expression in murine livers. (n=3/group) (E)GRHL2 mRNA expression and correlation with MIR122 expression in human livers (n=10–12/group). Student’s t-test, two-way ANOVA, and Pearson’s correlation coefficient.