Figure 2. Characteristics of mutations detected in plasma.

Libraries were prepared and sequencing conducted using a 61-gene panel to detect cancer-associated mutations. Shown are A. allele fractions of 16 variants detected in the plasma of 12 patients (horizontal line indicates median=29.1%, range 1.1 to 63.2%), and B. the allele fraction for each mutation detected, with mutations grouped by gene for most frequently detected mutations. Patient numbers are listed along the y-axis.