Table 1.
All Patients (n = 25) |
Patients with Mutation Detected in ctDNA (n = 12) |
||||
---|---|---|---|---|---|
Number | %1 | Number | %2 | P-value | |
Mean age (+/− SD) | 57.6 (+/− 16.3) | – | 57.0 (+/− 13.7) | – | 0.873 |
Sex | |||||
Male | 18 | 72 | 8 | 44 | 0.673 |
Female | 7 | 28 | 4 | 57 | |
Disease state at blood draw | |||||
Active | 22 | 88 | 12 | 55 | 0.220 |
NED/Inactive | 3 | 12 | 0 | 0 | |
Disease stage at blood draw | |||||
IIIa | 1 | 4 | 0 | 0 | 0.480 |
IIIb | 2 | 8 | 0 | 0 | |
IIIc | 1 | 4 | 1 | 100 | |
IV | 21 | 84 | 11 | 52 | |
Received any prior therapy | |||||
Yes | 21 | 84 | 11 | 52 | 0.593 |
No | 4 | 16 | 1 | 25 | |
Receiving therapy at time of blood draw | |||||
Yes | 17 | 68 | 9 | 53 | 0.673 |
No | 8 | 32 | 3 | 38 | |
Total number of previous therapeutic regimens | |||||
0 | 4 | 16 | 1 | 25 | 0.304 |
1–2 | 14 | 56 | 6 | 43 | |
≥ 3 | 7 | 28 | 5 | 71 | |
Received chemotherapy prior to blood draw | |||||
Yes | 2 | 8 | 2 | 100 | 0.220 |
No | 23 | 92 | 10 | 44 | |
Received TKI prior to blood draw | |||||
Yes | 6 | 24 | 3 | 50 | 1.000 |
No | 19 | 76 | 9 | 47 | |
Received checkpoint inhibitor prior to blood draw | |||||
Yes | 16 | 64 | 9 | 56 | 0.411 |
No | 9 | 36 | 3 | 33 | |
Received radiation prior to blood draw | |||||
Yes | 10 | 40 | 7 | 70 | 0.111 |
No | 15 | 60 | 5 | 33 |
The denominator for this % calculation is the n=25 total patients included in this table.
The denominator for this % calculation varies row by row. It is the number of total patients shown in the left-most column for that row’s patient category.