Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2017 Oct 23;31(1):73–81. doi: 10.1111/pcmr.12623

Table 1.

Patient characteristics

All Patients
(n = 25)
Patients with Mutation Detected in ctDNA
(n = 12)
Number %1 Number %2 P-value
Mean age (+/− SD) 57.6 (+/− 16.3) 57.0 (+/− 13.7) 0.873
Sex
 Male 18 72 8 44 0.673
 Female 7 28 4 57
Disease state at blood draw
 Active 22 88 12 55 0.220
 NED/Inactive 3 12 0 0
Disease stage at blood draw
 IIIa 1 4 0 0 0.480
 IIIb 2 8 0 0
 IIIc 1 4 1 100
 IV 21 84 11 52
Received any prior therapy
 Yes 21 84 11 52 0.593
 No 4 16 1 25
Receiving therapy at time of blood draw
 Yes 17 68 9 53 0.673
 No 8 32 3 38
Total number of previous therapeutic regimens
 0 4 16 1 25 0.304
 1–2 14 56 6 43
 ≥ 3 7 28 5 71
Received chemotherapy prior to blood draw
 Yes 2 8 2 100 0.220
 No 23 92 10 44
Received TKI prior to blood draw
 Yes 6 24 3 50 1.000
 No 19 76 9 47
Received checkpoint inhibitor prior to blood draw
 Yes 16 64 9 56 0.411
 No 9 36 3 33
Received radiation prior to blood draw
 Yes 10 40 7 70 0.111
 No 15 60 5 33
1

The denominator for this % calculation is the n=25 total patients included in this table.

2

The denominator for this % calculation varies row by row. It is the number of total patients shown in the left-most column for that row’s patient category.