Table 1.
Metachronous findings by patient characteristics from the index colonoscopy among 5,433 NHCR participants with 2 colonoscopies (1/2004 – 6/2015)
| Metachronous | |||||
|---|---|---|---|---|---|
| HRA | SP ≥ 1 cm | ||||
| Total N = 5,433 | No N = 4,987 (91.8%) | Yes N = 446 (8.2%) | No N = 5,368 (98.8%) | Yes N = 65 (1.2%) | |
| Characteristics1 | N (col %) | N (col %) | N (col %) | N (col %) | N (col %) |
| Age at index colonoscopy (in years) | p<0.0001 | p=0.28 | |||
| 40–49 | 661 (12.2) | 630 (12.6) | 31 (6.9) | 656 (12.2) | 5 (7.7) |
| 50–59 | 2,241 (41.3) | 2,098 (42.1) | 143 (32.1) | 2,207 (41.1) | 34 (52.3) |
| 60–69 | 1,756 (32.3) | 1,586 (31.8) | 170 (38.1) | 1,743 (32.4) | 17 (26.2) |
| 70+ | 775 (14.3) | 673 (13.5) | 102 (22.9) | 766 (14.3) | 9 (13.8) |
| Gender | p<0.0001 | p=0.56 | |||
| Female | 2,731 (50.3) | 2,573 (51.6) | 158 (35.4) | 2,696 (50.2) | 35 (53.8) |
| Male | 2,702 (49.7) | 2,414 (48.4) | 288 (64.6) | 2,672 (49.8) | 30 (46.2) |
| Family history of CRC | p=0.07 | p=0.95 | |||
| No | 4,046 (80.4) | 3,706 (80.1) | 340 (83.7) | 4,000 (80.4) | 46 (80.7) |
| Yes | 988 (19.6) | 922 (19.8) | 66 (16.3) | 977 (19.6) | 11 (19.3) |
| Current smoking status | p=0.63 | p=0.19 | |||
| No | 4,346 (90.4) | 3,996 (90.5) | 350 (89.7) | 4,300 (90.5) | 46 (85.2) |
| Yes | 460 (9.6) | 420 (9.5) | 40 (10.3) | 452 (9.5) | 8 (14.8) |
| BMI | p=0.05 | p=0.83 | |||
| < 25 (Underweight and normal) | 1,293 (27.3) | 1,210 (27.6) | 83 (21.7) | 1,279 (27.2) | 14 (25.5) |
| 25 to < 30 (Overweight) | 1,854 (38.9) | 1,702 (38.8) | 152 (39.7) | 1,831 (38.9) | 23 (41.8) |
| 30 to < 35 (Obesity class I) | 1,051 (22.1) | 958 (21.9) | 93 (24.3) | 1,041 (22.1) | 10 (18.2) |
| 35 (Obesity classes II and III) | 567 (11.9) | 512 (11.7) | 55 (14.4) | 559 (11.9) | 8 (14.6) |
| Median time interval between colonoscopies (in years) | p=0.004 | p=0.06 | |||
| < 4.9 | 2,716 (50.0) | 2,464 (49.4) | 252 (56.5) | 2,676 (49.9) | 40 (61.5) |
| >= 4.9 | 2,717 (50.0) | 2,523 (50.6) | 194 (43.5) | 2,692 (50.1) | 25 (38.5) |
Abbreviation: NHCR = New Hampshire Colonoscopy Registry, CRC = colorectal cancer, BMI = body mass index, HRA=high risk adenoma, SP = serrated polyp
1
Missing (N): family history of CRC (399), current smoking status (627), BMI (668)