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DDI prediction using the static model
| Substrate | [I] | DDI Prediction | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| RLM | SRH | |||||||
|
| ||||||||
| Replot | Numerical | Replot | Numerical | |||||
|
| ||||||||
| All data | Linear data | Seq | All data | Linear data | Direct | Seq | ||
| MDZ (IV) | Isys | 10.7 | 11.3 | 4.8 | 8.2 | 10.6 | 2.7 | 3.1 |
| Isys,u | 2.8 | 2.9 | 1.3 | 1.7 | 2.3 | 1.1 | 1.1 | |
|
| ||||||||
| MDZ (oral) | Ih | 5.9 | 6.1 | 2.1 | 3.3 | 4.9 | 1.5 | 1.6 |
| Ih,u | 1.6 | 1.6 | 1.3 | 1.4 | 1.5 | 1.3 | 1.3 | |
