Table 2.
Distribution of the inner retinal layer thicknesses in the study population
| Control Group |
AREDS-2 | AREDS-3 | P* | |
|---|---|---|---|---|
| Mean RNFL thickness | ||||
| Central 1mm2 | 12.8±1.8 | 13.5±2.1 | 12.6±2.3 | 0.60 |
| Superior | 23.1±1.1 | 24.0±3.2 | 24.6±3.5 | 0.12 |
| Temporal | 17.8±1.5 | 17.6±1.5 | 18.2±2.0 | 0.55 |
| Inferior | 25.0±2.7 | 25.0±2.8 | 23.7±3.4 | 0.23 |
| Nasal | 20.4±2.3 | 20.5±2.5 | 20.9±2.2 | 0.62 |
| Total Average | 19.8±0.2 | 20.1±0.3 | 20.0±0.34 | 0.85 |
| Mean GGL thickness | ||||
| Central 1mm2 | 14.7±2.8 | 15.8±3.4 | 15±3.1 | 0.52 |
| Superior | 50.4±5.4 | 48.4±5.3 | 48.1±4.8 | 0.17 |
| Temporal | 44.7±5.3 | 43.5±5.4 | 42.7±5.2 | 0.15 |
| Inferior | 50.6±5 | 48.4±5.1 | 48.2±5.9 | 0.04 |
| Nasal | 49.3±5.8 | 48.5±5.7 | 47.2±7.6 | 0.10 |
| Total Average | 41.9±0.8 | 40.9±0.8 | 40.2±0.8 | 0.14 |
| Mean IPL thickness | ||||
| Central-1mm2 | 20.9±2.9 | 21.8±3.2 | 20.5±3.4 | 0.37 |
| Superior | 39.7±3.9 | 38.1±4.6 | 37.4±3.2 | 0.07 |
| Temporal | 40.9±3.3 | 39.3±4 | 37.6±3.7 | 0.003 |
| Inferior | 40.2±3.1 | 38.3±4 | 37.3±3.5 | 0.010 |
| Nasal | 41.8±3.4 | 39.8±4.3 | 38.6±4.1 | 0.009 |
| Total average | 36.7±0.5 | 35.5±0.7 | 34.3±0.5 | 0.02 |
RNFL=retina nerve fiber layer, GCL=ganglion cell layer, IPL=inner plexiform layer, superior=
Total average=mean thickness within 3 mm of Early Treatment Diabetic Retinopathy Study circle
Variables are represented in microns as mean ±standard deviation, p= p value,
*
one-way ANOVA
Note, there is no significant difference in any retina layer thickness between control subjects and AREDS-2 group.