Table 1.
Controls (N=32) Mean ± SD |
Welders (N=48) Mean ± SD |
Raw p-values |
|
---|---|---|---|
I. Demographics | |||
Age (years) | 43.4 ± 11.2 | 48.0 ± 10.8 | 0.075 |
Education (years) | 16.2 ± 2.4 | 12.8 ± 1.7 | <0.001 |
ALT (IU/L) | 37.7 ± 16.5 | 39.8 ± 16.7 | 0.684 |
BMI (kg/m2) | 26.0 ± 3.3 | 29.2 ± 5.3 | 0.004 |
Hemoglobin | 14.8 ± 0.8 | 15.2 ± 1.0 | 0.102 |
Smokers (%) | 3.2% | 15.2% | 0.091 |
Cigarettes/day (no.) | 13.0 ± 12.0 | 20.2 ± 13.5 | 0.303 |
UPDRS-I | 1.0 ± 1.9 | 1.7 ± 2.0 | 0.125 |
UPDRS-II | 3.9 ± 3.1 | 4.6 ± 3.5 | 0.383 |
UPDRS-III | 1.5 ± 2.1 | 1.9 ± 2.4 | 0.461 |
| |||
II. Exposure metrics and Blood Metal levels | |||
HrsW (hours) | 0 ± 0 (0) | 248 ± 195 | <0.001 |
E90 mg-days/m3 | 0.0027 ± 0 | 2.4 ± 2.0 | <0.001 |
YrsW (years) | 0 ± 0 (0) | 25.8 ± 10.6 | <0.001 |
ELT mg-years/m3 | 0.0013 ± 0.0004 | 1.2± 0.8 | <0.001 |
Mn (ng/mL) | 8.8 ± 2.5 | 10.7 ± 3.2 | <0.001 |
Fe (μg/mL) | 498 ± 75 | 551 ± 56 | <0.001 |
Data represent the mean ± SD. Demographic (I) and blood metal (II) measures were compared between controls and welders using analysis of variance (ANOVA) for demographic and blood metal data. Abbreviations: ALT-alanine aminotransferase; BMI-body mass index; UPDRS-Unified Parkinson’s Disease Rating Scale-motor scores.