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. 2017 Dec 19;11:706. doi: 10.3389/fnins.2017.00706

Figure 2.

Figure 2

Simulation of DWI schemes and derived parameters. All estimated DWI parameters, including eccentricity (A), restricted fraction (B), and ADC|| from the DDE (C) or SDE (D), exhibited high sensitivity to the injured axon fraction (x-axis) with minimal differences between different intra-axonal volume fractions (shown as individual lines). Notably, ADC|| was nearly identical between the DDE and SDE (E) for uniformly-oriented fibers. The estimated parameters showed differential reliability under low SNR with ADC|| being most robust to noise (F).