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. 2017 Dec 19;9:421. doi: 10.3389/fnagi.2017.00421

FIGURE 4.

FIGURE 4

Immunofluorescence expression of NF-κB, TNF-α, iNOS, and ICAM in SNpc. of CONT, MPTP, and MPTP+Mp mice by using Image J Software at 20x magnification. The MPTP intoxicated PD mice showed significantly enhanced expression level of NF-κB (A), TNF-α (B), iNOS (C), and ICAM (D) positive cells as compared to control. On Mp supplementation in PD mice showed significantly alleviated expression level of NF-κB, TNF-α, iNOS, and ICAM positive cells as compared to MPTP mice. Values are expressed as mean ± SEM of integrated fluorescent value (IFV) (∗p < 0.05, ∗∗p < 0.01, n = 3). ns, non-significant; TNF-α, tumor necrosis factor alpha; iNOS, inducible nitric oxide synthase; ICAM, intercellular adhesion molecule 1; SNpc, substantia nigra pars compacta.