Figure 4.
The effect of formyl peptide receptor 2 (Fpr2) and fibroblast growth factor receptor 1 (FGFR1) on Müller glial cell (MGC) proliferation in the presence or absence of high glucose (HG). MGC proliferation was examined in the presence of cathelin-related antimicrobial peptide (CRAMP) (10−6 M) or b-FGF (10 ng/ml) under normal glucose (NG) or HG for 24, 48, and 72 h. (A–D) CRAMP-induced MGC proliferation under HG or NG condition. (E–H) b-FGF-induced MGC proliferation under HG or NG condition. Graphs represent the mean ± SEM of triplicate samples (n = 3). *Indicates significantly (p < 0.05) increased MGC proliferation in HG compared with the cells in NG. #Indicates significantly (p < 0.05).