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Levels of dhSph and dhS1P are reduced in brain tissues from R6/2 mice. Lipidomic analysis by LC-MS/MS of dhSph and dhS1P in striatal (A,C) and cortical (B,D) tissues from manifest (11-week old) R6/2 mice and wild type littermates. Values are represented as mean ± SD. N = 7–10 for each group of mice. For statistical analyses, Two-tailed Unpaired t-test was used; p < 0.05 were considered significant.
