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. Author manuscript; available in PMC: 2017 Dec 24.
Published in final edited form as: Pharmacol Biochem Behav. 2016 Aug 26;152:20–29. doi: 10.1016/j.pbb.2016.08.008

Fig. 6.

Fig. 6

Adult social and anxiety-like behaviors are not affected by early PO exposure. Male and female pups exposed to PO were retested for social and anxiety-like behaviors in adulthood. (A) Distance traveled was greater among unexposed females and decreased in both males and females exposed to PO. (B) Unexposed females also displayed more entries in the center zone, whereas PO exposed male and females entered this zone less. (C) Time spent in the center zone did not significantly differ between groups. (D) The interaction ratio of the SIT showed no significant effects of either variable. In the EPM, groups did not differ with respect to (E) time spent in the open arms or (F) number of entries in the open arms of the elevated plus maze. Behavior in the L/D box showed no significant effect of any condition on (G) time spent in the light zone or (H) number of entries into the light zone of the light/dark box. (Data expressed as mean ± SEM. For OFT, EPM and L/D Box control male group, n = 6; PO male group, n = 6; control female group, n = 6; PO female group, n = 6; for SIT control male group, n = 4; PO male group, n = 6; control female group, n = 4; PO female group n = 6 two-way ANOVA.)