Table 2.
Selected genes identified by RNA-Seq analysis.
| Locus | Description* | Ratio (D/M)# | P-value |
|---|---|---|---|
| SMU.265 | Putative amino acid kinase | 1.56 | 0.016654713 |
| SMU.270 | Unknown | 1.67 | 0.000835434 |
| SMU.629 | Mn-dependent Superoxide dismutase, SodA, | 1.60 | 2.48242E-08 |
| SMU.910 | Glucosyltransferase-S, GtfD | 1.50 | 1.98036E-14 |
| SMU.924 | Lipid hydroperoxide peroxidase, Tpx | 1.67 | 1.5412E-12 |
| SMU.1117 | NADH oxidase (H2O-forming), Nox1, Nox | 2.09 | 5.75842E-26 |
| SMU.1339 | Putative bacitracin synthetase | 1.65 | 6.9306E-08 |
| SMU.1340 | Putative surfactin synthetase | 1.72 | 2.61792E-10 |
| SMU.1342 | Putative bacitracin synthetase, BacA | 1.92 | 5.72903E-15 |
| SMU.1346 | Putative thioesterase, BacT | 2.15 | 2.98087E-12 |
| SMU.1425 | Putative Clp proteinase, ATP-binding subunit, ClpB | 1.53 | 0.008209022 |
| SMU.2028 | Levansucrase precursor, beta-D-fructosyltransferase, Ftf, SacB | 1.72 | 7.67161E-26 |
| SMU.20 | Unknown (MreC, putative cell shape determining protein) | −1.61 | 2.98587E-05 |
| SMU.183 | Putative Mn/Zn ABC transporter | −1.65 | 0.011069851 |
| SMU.184 | Putative ABC transporter metal binding lipoprotein | −1.69 | 7.99849E-07 |
| SMU.1004 | Gucosyltransferase-I, GtfB | −1.50 | 1.11398E-16 |
| SMU.1997 | Transcriptional regulator ComX, alternative sigma factor | −1.59 | 9.38051E-05 |
| SMU.2042 | Dextranase precursor | −1.66 | 3.37282E-19 |
*
Description and putative function of the identified genes are based on the published S. mutans database.
#
Defined as relative levels of expression in the dual-species over those in the mono-species with “–” indicating the down-regulated genes.