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Effect of TRPC6 knockdown on the responsiveness to 4-AP. As compared to control siRNA-infused animals, TRPC6 siRNA-infused animals reveal lower responsiveness to 4-AP. (A) Representative EEG traces and frequency-power spectral temporal maps in response to 4-AP. (B) Quantification of total EEG power in response to 4-AP (mean ± SEM; *p < 0.05 vs. control siRNA; n = 7, respectively).
