Table 1. Clinical characteristics of the study subjects.
| Characteristic | Total | CAD (−) | CAD (+) | p value |
|---|---|---|---|---|
| (n = 233) | (n = 43) | (n = 190) | ||
| Age, years | 67.3 ± 10.8 | 63.8 ± 11.9 | 68.0 ± 10.5 | 0.020 |
| Male, n (%) | 140 (60.1) | 17.0 (39.5) | 123 (64.7) | 0.002 |
| Body mass index (kg/m2) | 24.5 ± 4.1 | 24.9 ± 4.9 | 24.4 ± 3.9 | 0.435 |
| Risk factors, n (%) | ||||
| Hypertension | 148 (63.5) | 22 (51.2) | 126 (66.3) | 0.062 |
| Diabetes mellitus | 91 (39.1) | 8 (18.6) | 83 (43.7) | 0.002 |
| Dyslipidemia | 75 (32.2) | 9 (20.9) | 66 (34.7) | 0.080 |
| Smoking | 53 (22.7) | 5 (11.6) | 48 (25.3) | 0.054 |
| Pretest probability, n (%) | ||||
| Low (< 10%) | 10 (4.3) | 3 (7.0) | 7 (3.7) | |
| Intermediate (10%–89%) | 195 (83.7) | 37 (86.0) | 158 (83.2) | 0.362 |
| High (> 90%) | 28 (12.0) | 3 (7.0) | 25 (13.2) | |
| Laboratory findings | ||||
| Hemoglobin, g/dl | 13.5 ± 7.3 | 13.1 ± 1.6 | 13.6 ± 8.0 | 0.670 |
| Estimated GFR, mL/min/1.73 m2 | 74.7 ± 26.1 | 78.0 ± 26.1 | 73.9 ± 26.1 | 0.361 |
| Total cholesterol, mg/dl | 158 ± 46 | 163 ± 39 | 157 ± 47 | 0.446 |
| LDL cholesterol, mg/dl | 99.0 ± 50.6 | 97.1 ± 34.9 | 99.5 ± 53.6 | 0.786 |
| HDL cholesterol, mg/dl | 42.7 ± 12.3 | 47.3 ± 13.7 | 41.6 ± 11.8 | 0.008 |
| Triglyceride, mg/dl | 131 ± 86 | 108 ± 58 | 136 ± 90 | 0.014 |
| C-reactive protein, mg/dl | 0.73 ± 1.89 | 0.49 ± 1.34 | 0.78 ± 1.99 | 0.377 |
| HbA1c, % | 6.87 ± 1.72 | 6.26 ± 0.99 | 7.0 ± 1.81 | 0.007 |
CAD, coronary artery disease; GFR, glomerular filtration rate; LDL, low-density lipoprotein; HDL, high-density lipoprotein.