Table 3. Genotype and allele distributions in obesity, ischemic heart disease, hypertension, dyslipidemia, and diabetes.
SNPs | Genotype | Obesity |
Ischemic heart disease |
Hypertension |
Dyslipidemia |
Diabetes |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
≥ 25 | < 25 | p value | (−) | (+) | p value | (−) | (+) | p value | (−) | (+) | p value | (−) | (+) | p value | ||
rs753152 | Major Homo | 7823 | 2755 | 0.729 | 12006 | 374 | 0.774 | 6624 | 3889 | 0.432 | 6396 | 3676 | 0.846 | 7496 | 561 | 0.030 |
74.0% | 26.0% | 97.0% | 3.0% | 63.0% | 37.0% | 63.5% | 36.5% | 93.0% | 7.0% | |||||||
Hetero+ | 561 | 191 | 883 | 29 | 482 | 265 | 476 | 278 | 526 | 55 | ||||||
Minor Homo | 74.6% | 25.4% | 96.8% | 3.2% | 64.5% | 35.5% | 63.1% | 36.9% | 90.5% | 9.5% | ||||||
rs77035639 | Major Homo | 8097 | 2840 | 0.643 | 12447 | 388 | 0.678 | 6864 | 4009 | 0.832 | 6642 | 3810 | 0.414 | 7758 | 589 | 0.163 |
74.0% | 26.0% | 97.0% | 3.0% | 63.1% | 36.9% | 63.5% | 36.5% | 92.9% | 7.1% | |||||||
Hetero+ | 287 | 106 | 442 | 15 | 242 | 145 | 230 | 144 | 264 | 27 | ||||||
Minor Homo | 73.0% | 27.0% | 96.7% | 3.3% | 62.5% | 37.5% | 61.5% | 38.5% | 90.7% | 9.3% | ||||||
rs3815524 | Major Homo | 7423 | 2587 | 0.301 | 11399 | 351 | 0.388 | 6275 | 3673 | 0.878 | 6067 | 3473 | 0.498 | 7105 | 554 | 0.323 |
74.2% | 25.8% | 97.0% | 3.0% | 63.1% | 36.9% | 63.6% | 36.4% | 92.8% | 7.2% | |||||||
Hetero+ | 961 | 359 | 1490 | 52 | 831 | 481 | 805 | 481 | 917 | 62 | ||||||
Minor Homo | 72.8% | 27.2% | 96.6% | 3.4% | 63.3% | 36.7% | 62.6% | 37.4% | 93.7% | 6.3% | ||||||
rs75380157 | Major Homo | 7718 | 2721 | 0.632 | 11878 | 366 | 0.349 | 6541 | 3835 | 0.611 | 6316 | 3634 | 1.000 | 7381 | 573 | 0.395 |
73.9% | 26.1% | 97.0% | 3.0% | 63.0% | 37.0% | 63.5% | 36.5% | 92.8% | 7.2% | |||||||
Hetero+ | 666 | 225 | 1011 | 37 | 565 | 319 | 556 | 320 | 641 | 43 | ||||||
Minor Homo | 74.7% | 25.3% | 96.5% | 3.5% | 63.9% | 36.1% | 63.5% | 36.5% | 93.7% | 6.3% | ||||||
rs574603859 | Major Homo | 8001 | 2777 | 0.012 | 12255 | 385 | 0.803 | 6778 | 3932 | 0.085 | 6550 | 3759 | 0.575 | 7648 | 587 | 0.921 |
74.2% | 25.8% | 97.0% | 3.0% | 63.3% | 36.7% | 63.5% | 36.5% | 92.9% | 7.1% | |||||||
Hetero+ | 383 | 169 | 634 | 18 | 328 | 222 | 322 | 195 | 374 | 29 | ||||||
Minor Homo | 69.4% | 30.6% | 97.2% | 2.8% | 59.6% | 40.4% | 62.3% | 37.7% | 92.8% | 7.2% | ||||||
rs147565266 | Major Homo | 8345 | 2932 | 1.000 | 12833 | 402 | 1.000 | 7079 | 4129 | 0.111 | 6841 | 3933 | 0.570 | 7981 | 611 | 0.378 |
74.0% | 26.0% | 97.0% | 3.0% | 63.2% | 36.8% | 63.5% | 36.5% | 92.9% | 7.1% | |||||||
Hetero+ | 39 | 14 | 56 | 1 | 27 | 25 | 31 | 21 | 41 | 5 | ||||||
Minor Homo | 73.6% | 26.4% | 98.2% | 1.8% | 51.9% | 48.1% | 59.6% | 40.4% | 89.1% | 10.9% |
Homo, homozygote; Hetero, heterozygote.