Supplementary Table 2. Allele and genotype frequencies of the RAMP2 and CLR genes in the participants.

SNP	Allele frequency	Genotype frequency	n	P for Hardy-Weinberg equilibrium
rs753152 (T/G)
TT	T = 0.965	T/T = 0.933	13137
TG		T/G = 0.065	921	0.003
GG	G = 0.035	G/G = 0.002	29
rs77035639 (A/G)
AA	A = 0.983	A/A = 0.965	13604
AG		A/G = 0.034	476	0.177
GG	G = 0.017	G/G = 0.001	7
rs3815524 (G/C)
GG	G = 0.940	G/G = 0.885	12464
GC		G/C = 0.110	1552	0.003
CC	C = 0.060	C/C = 0.005	71
rs75380157 (A/T)
AA	A = 0.959	A/A = 0.921	12978
AT		A/T = 0.076	1073	0.006
TT	T = 0.041	T/T = 0.003	36
rs574603859 (A/T)
AA	A = 0.975	A/A = 0.952	13405
AT		A/T = 0.047	664	0.001
TT	T = 0.025	T/T = 0.001	18
rs147565266 (T/A)
TT	T = 0.998	T/T = 0.996	14024
TA		T/A = 0.004	63	0.790
AA	A = 0.002	A/A = 0.000	0