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. Author manuscript; available in PMC: 2018 Sep 27.
Published in final edited form as: Chem Rev. 2017 Jun 5;117(18):11894–11951. doi: 10.1021/acs.chemrev.7b00022

Figure 45.

Figure 45

The total syntheses of two highly oxidized taxanes. Inspired by nature’s use of distinct cylcase and oxidase phases, the synthetic strategy features a number of selective oxidation reactions.237