Table 2.

Correlation between circulating cathepsin D levels and clinical parameters.

Variables	All subjects (n = 196)		Control (n = 98)		Case (n = 98)
	Coefficient	P value	Coefficient	P value	Coefficient	P value
Age (years)	−0.01	0.87	−0.01	0.90	−0.02	0.85
BMI (kg/m2)	0.19	0.01	0.10	0.31	0.12	0.23
Systolic BP (mmHg)	0.08	0.27	0.05	0.60	0.01	0.97
Diastolic BP (mmHg)	0.04	0.61	−0.03	0.74	−0.01	0.97
Total cholesterol (mmol/l)	0.07	0.33	0.04	0.69	0.02	0.86
Triglyceride (mmol/l)	0.18	0.01	0.17	0.10	0.15	0.15
LDL cholesterol (mmol/l)	0.04	0.60	0.12	0.25	−0.15	0.15
HDL cholesterol (mmol/l)	−0.02	0.74	0.06	0.56	−0.07	0.50
HbA1c (%)	0.16	0.02	−0.04	0.69	0.02	0.86
Fasting glucose (mmol/l)	0.26	<0.01	−0.01	0.99	0.19	0.06
HOMA-IR	0.29	<0.01	0.02	0.33	0.25	0.01
HOMA-IS	0.09	0.22	0.13	0.19	0.02	0.84

Circulating cathepsin D levels were log-transformed variable. BMI: body mass index; BP: blood pressure; HbA_1c: hemoglobin A1c; LDL: low-density lipoprotein; HDL: high-density lipoprotein; HOMA-IR: homeostasis model assessment of insulin resistance; HOMA-IS: homeostasis model assessment of insulin secretion.