. 2017 Dec 11;2017:3458356. doi: 10.1155/2017/3458356

Table 2.

Factors for visual prognosis in middle-aged and elderly patients with optic neuritis.

Factors		Number of patients with final VA < 20/400	Number of patients with final VA ≥ 20/400	p value
Initial BCVA	>20/400	3	16	0.001^∗
Initial BCVA	<20/400	35	22	0.001^∗
Sex	Male	15	17	NS
Sex	Female	23	21	NS
Age	<65	31	37	NS
Age	≥65	7	1	NS
Laterality	Unilateral	24	29	NS
Laterality	Bilateral	14	9	NS
Initial disc appearance	Normal	23	21	NS
Initial disc appearance	Swollen	14	16	NS
Systemic association	Normal	20	23	NS
Systemic association	Abnormal	10	11	NS
CSF	Normal	10	12	NS
CSF	Abnormal	13	11	NS
Serum AQP4-Ab status	Seropositive	7	3	NS
Serum AQP4-Ab status	Seronegative	17	22	NS
Orbital MRI	Normal	4	5	NS
Orbital MRI	Abnormal	22	22	NS
Brain MRI	Normal	11	15	NS
Brain MRI	Abnormal	13	11	NS
pRNLF	Average	64.00 ± 12.91	68.58 ± 18.70	NS
	Superior	69.52 ± 20.72	79.23 ± 32.63	NS
	Nasal	59.60 ± 9.39	60.35 ± 10.00	NS
	Inferior	72.88 ± 23.53	83.88 ± 30.37	NS
	Temporary	50.85 ± 15.81	52.92 ± 10.15	0.045^∗

BCVA: best corrected visual acuity; CF: count finger; CSF: cerebrospinal fluid; AQP4-Ab: anti-aquaporin-4 antibody; MRI: magnetic resonance imaging; pRNLF: peripapillary retinal nerve fibre layer, NS: nonsignificant; ^∗p < 0.05.